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Combat COVID is a one-stop resource created by the U.S. Department of Health and Human Services (HHS) to help us all win the fight against COVID-19.

Combat COVID empowers all people to take action against COVID-19—right now. The website offers science-based facts and practical tips about vaccines, monoclonal antibodies, and how to take part in research studies (known as clinical trials) for COVID-19 treatments.

The clinical trials described on Combat COVID are supported through a public/private partnership—coordinated by the Foundation for the National Institutes of Health—called Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV). ACTIV’s goal is to discover safe and effective treatments and vaccines for COVID-19. https://www.nih.gov/research-training/medical-research-initiatives/activ

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Combat COVID is part of the Federal COVID Response, a partnership among several HHS agencies and the Department of Defense. The HHS agencies involved include:

● Centers for Disease Control and Prevention
● U.S. Food and Drug Administration (FDA)
● National Institutes of Health (NIH)
● Biomedical Advanced Research and Development Authority

The Combat COVID website describes the objectives of each ACTIV clinical trial (and associated trials supported by NIH) across the United States, as well as where each clinical trial is located.

Combat COVID also offers two helplines to answer questions in English and Spanish about clinical trials for COVID-19 treatments (1-877-414-8106) and about monoclonal antibodies (1-877-332-6585).


Monoclonal antibodies

The ACTIV and ACTIV-associated trials are testing monoclonal antibodies, antivirals, anticoagulants, immunomodulators, and convalescent plasma, among other treatments that have been authorized by the FDA for treating COVID-19.

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These trials are recruiting:

● People who have not been exposed to the novel coronavirus that causes COVID-19
● People who have been exposed to the novel coronavirus but have not developed symptoms yet
● Hospitalized adult patients with COVID-19
● People at every other stage of COVID-19 illness

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Clinical trials are at the heart of many medical discoveries. They are the key to protecting our communities now and in the future.

COVID-19 has impacted every population, and it has hit the Black and Hispanic/Latino populations especially hard. This is largely due to social and economic factors that affect some communities more than others.

Many people of color have participated and are participating in the ACTIV clinical trials, and more participants of color are needed to ensure that COVID-19 treatments are effective for everyone.