Our bodies naturally make antibodies to fight infection. mAbs are made in a lab and given to people directly through an intravenous (IV) infusion.
mAb treatments authorized by the U.S. Food and Drug Administration (FDA) for emergency use may help people who are at high risk for serious symptoms of the disease to:
a) Reduce the likelihood of being hospitalized
b) Recover faster from COVID-19
mAbs are designed for people who:
a) Have tested positive for COVID-19, and
b) Have mild to moderate symptoms of the disease for 10 days or less, and
c) Are at high risk of becoming seriously ill. To learn more, visit our page How Do I Know If I’m High Risk, and What Do I Do Next?
mAb treatment must be given within 10 days of a person’s first symptoms of COVID-19. The sooner a person receives mAb treatment, the better.
mAb treatments are experimental. However, they have received Emergency Use Authorization (EUA) from the FDA, and more than 300,000 people have been treated with mAbs. Researchers continue to study mAb treatments for safety and effectiveness.
Three mAb treatments have received EUA from the FDA: bamlanivimab, the combination of casirivimab and imdevimab, and the combination of bamlanivimab and etesevimab. All three treatments are given with an IV infusion.
The three treatments are designed in a very similar way, with the same goal: to prevent the virus that causes COVID-19 from entering human cells.
The treatments are offered at approximately 5,000 infusion locations across the United States. These include infusion centers, urgent care clinics, and emergency rooms.
Different infusion locations have different amounts of the treatments available, so some of them may not be administering more treatments. Your healthcare provider can help you find a location near you, and can contact the infusion location to refer you for treatment.
You can learn more about mAb treatments on our page Monoclonal Antibodies for High-Risk COVID-19 Positive Patients.
If you think you may qualify for mAb treatments and want to ask about getting treatment, contact your healthcare provider.
Your healthcare provider may decide you don’t qualify for mAb treatment. There could be several reasons for this. You may not meet all of the eligibility criteria, or you may have an underlying health condition that disqualifies you for mAb treatment.
Whatever the reason is, don’t give up. There could be another option. You may be able to join a clinical trial for COVID-19 treatments.
Participants in these clinical trials may receive new drugs or other treatments, so scientists can evaluate how well the treatments work. Thousands of participants in clinical trials have helped with the discovery of new treatments for COVID-19, and many more participants are needed to ensure that treatments work for people across age, gender, race, and ethnicity.
Ask your healthcare provider if you may be eligible for a clinical trial for treating COVID-19. To learn more about clinical trials, visit our page, You Can Help Combat COVID, or call 877-414-8106.